KMID : 0942820080070020133
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Journal of Korean Brain Tumor Society 2008 Volume.7 No. 2 p.133 ~ p.137
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Complications of Gamma Knife Radiosurgery for Vestibular Schwannoma
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Lee Dong-Hyun
Park Seong-Hyun Park Jae-Chan Hwang Jeong-Hyun Yoon Kyung-Hyeok Hwang Sung-Kyoo
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Abstract
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Objectives:The treatment of vestibular schwannoma(VS) is challenging due to a high morbidity rate after microsurgery. On the other hand, gamma knife radiosurgery(GKRS) is regarded as an alternative treatment method for VS due to its low morbidity rate. The authors retrospectively analyzed the complications of GKRS to evaluate the therapeutic usefulness of GKRS in VS.
Methods: Complications were analyzed retrospectively in 33 cases of VS treated by GKRS at our hospital from March 2005 to May 2008 in terms of patient age, prescription dose, and tumor size,
Results: Major complications, such as, signs of increased ICP or ataxia developed in 4 patients, and all had a tumor volume of more than 10 ml. Three of the four were treated by subtotal tumor resection. Hydrocephalus developed in four patients, and two underwent ventriculo-peritoneal shunt placement.
Conclusion: Early complications of GKRS in cases with a large VS were significant. Our results support a treatment strategy of subtotal tumor removal followed by scheduled radiosurgery or fractionated radiosurgery for the manage-ment of large VS.
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KEYWORD
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Vestibular schwannoma, Complication, Gamma knife radiosurgery, Hydrocephalus, Ataxia
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